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Onnit Total Mitochondria has been making waves ever since its launch. Users are thrilled with the results, claiming that it boosts their physical and mental energy during the day, without affecting their sleep. Because of its popularity, we were naturally included to do a thorough Onnit Total Mitochondria review.

Whereas most energy-boosting supplements use caffeine or other stimulants that cause side effects, Onnit Total Mitochondria uses a stimulant-free formula that naturally encourages your body to produce more energy.

Additionally, Onnit Total Mitochondria helps you with:

  • ATP Production – optimizes your mitochondria to produce more ATP, which is the energy currency of your body – resulting in a steady flow of energy. No crashes, no jitters.
  • Antioxidant protection – makes your cells more resilient to oxidative stress and improves their integrity.
  • Cardiovascular support – encourages healthy blood flow for optimal nutrient and oxygen delivery, along with a fighting plaque that builds up within your blood vessels.

The ingredients are all natural, vegan, and gmo-free. The benefits sound great, too! But how accurate are Onnit Total Mitochondria claims? Let’s find out.


Pros and Cons

Onnit Total Mitochondria is a great product.

It’s simple, doesn’t overcomplicate it with the ingredients, and focuses on what works. We also like that it doesn’t use stimulants like many other ‘energy’ supplements. Stimulants are disguised as energy boosters, but that energy kick is short-lived and is followed by a hard crash afterwards.

If you’re someone who wants to have more stable energy, both mental and physical, then a supplement like Onnit Total Mitochondria could be a game-changer. As we age, our levels of CoQ10 drop down, and with it, so does our energy and motivation.

Onnit Total Mitochondria provides CoQ10 along with a few other ingredients to support long-range energy production, leading to optimal performance.


  • Clean and safe formula
  • Patented and well-studied ingredients
  • Boosts your mitochondria and energy production, supports heart health and promotes longevity
  • Effective for mental focus too


  • Could use ALCAR and Bioperine for added benefits

Who Makes Total Mitochondria?

The company that produces Total Mitochondria is called Onnit. They’re one of the leading nootropic & wellness supplement companies in the USA. Onnit products are available on both the official site and Amazon, and are backed by famous people like Joe Rogan.

One thing that stood out to us about Onnit is its exceptional customer support. They offer a full 90-day money-back guarantee on their products, which signals that they’re confident in what they deliver.

Not only that, you don’t need to return the product if you aren’t happy with it. All you have to do is e-mail them and say it didn’t work for you – and they’ll get you your money back.


Most energy supplements nowadays are filled with caffeine. This gives you an illusion that the product works, after all, caffeine is a great alertness booster. But the problem is, this energy supply isn’t sustainable and often leaves you feeling groggy and down after a few hours.

Onnit Total Mitochondria has opted for another approach. Instead of using stimulants like caffeine, it has mitochondria-boosting ingredients that won’t cause side effects typically linked to stimulants.

If the claims on Onnit’s website are correct, their Total Mitochondria will help you by:

  • Increasing both mental and physical energy
  • Protecting cellular integrity
  • Promoting heart health
  • Enhancing antioxidant activity

Breathing, eating, sleeping… whatever you do, it triggers a certain metabolic process. The byproducts of these processes are often free radicals that cause oxidative stress and damage to your cells.

Our bodies are great at fending off these free radicals, but as we age, our defenses get weaker. Over time, this cell damage accumulates and we see more and more signs of aging. The good news is, we may help to slow down this process by providing additional protection to our cells in the form of antioxidants and other natural compounds.

This is where products like Onnit Total Mitochondria step in. Let’s see if it has the right ingredients to help you stay younger and fitter for longer.


The ingredient profile of Onnit Total Mitochondriaia is clean and effective. There are no unnecessary ingredients; in fact, there are only 3 of them. They work together to boost your cellular energy, promote blood flow, and support a healthy lifestyle.

onnit total mitochondria ingredients label


Resveratrol is one of nature’s most powerful antioxidants. It’s found in red wine and is thought to promote (1):

  • Antioxidant activity – supports heart health and blood flow to tissues, improves your recovery
  • Longevity – resveratrol is seen to promote lifespan in animals, and current evidence shows it might ‘add life to years’ in humans.
  • Energy – resveratrol boosts fat utilization in the body, helping you not only to have more energy but also lose weight.

Resveratrol is produced in the skin of grapes as a defense mechanism from toxins. It’s good for us in these small amounts because it protects your cells from damage linked to oxidation.

It also supports your mitochondria, which are tiny energy powerhouses in your cells that produce ATP.

ATP is what runs your body.

When your cells, and by extension, mitochondria are healthy, they’re able to produce optimal amounts of ATP.

Resveratrol is a great ingredient to see in Onnit Total Mitochondria. Although it’s not as strong at boosting energy as the other two ingredients in the formula, its main strength is promoting your heart health and longevity.


CoQ10 is one of the most popular ingredients in supplements out there. And there’s a good reason for that.

CoQ10 is shown to protect your cells from free radical damage. It’s particularly good at promoting a healthy heart and blood flow and is essential for your mitochondria to produce energy. (2)

Essentially, CoQ10 helps to improve cellular integrity and by doing so, helps you lead a healthier and more energetic lifestyle.

You’ll find CoQ10 in many foods. But organ meats and fatty fish are its best food sources. Supplementing CoQ10 has additional benefits for heart health and energy production. Especially as we get older, as that’s when our natural CoQ10 levels get down, and our need for this important nutrient increases.


Found in human milk and certain foods, PQQ boosts your mitochondria density and activity – providing a one-two punch to increase your energy production.

PQQ also works together with glutathione to protect your cells from oxidation. Which, just like with resveratrol, can add life to your years.

Anything Missing?

Although small, the Total Mitochondria formula is complete. It has three key ingredients that will support healthy energy production.

That said, some users might prefer a formula with added Bioperine and Acetyl-L-Carnitine. While these ingredients aren’t essential, they could’ve theoretically improved Total Mitochondria’s formula even further.

In any case, we’re happy with the ingredient profile of this product.

How to Take (Dosage)

The best dosage for Onnit Total Mitochondria is 1 capsule daily. You can take Onnit’s Total Mitochondria either with or without food.

The bottle will last you a full month with one daily serving.

The label also states that you should talk with a healthcare professional if you have any underlying medical condition. This is a rule you should follow no matter what supplement you’re planning to get.

Side Effects

The safety of a supplement mostly depends on its ingredients. Onnit Total Mitochondria has 3 ingredients, all of which are tested for safety and are shown to have no side effects at doses that Total Mitochondria uses.

All in all, it’s a clean and safe supplement, and most users will reap nothing but its benefits.


Currently, Onnit runs a deal where you can get Onnit Total Mitochondria for $50.99 instead of $59.99. The product is available on their official website, as well as on Amazon.

You can get an additional 15% off when you subscribe to Onnit on their website.

Is Onnit Total Mitochondria Good Value For Money?

Most definitely. The price of Onnit Total Mitochondria reflects its quality; it uses premium and patented ingredients that aren’t cheap to make. However, they bring much stronger benefits than most cheaper supplements that use side effect-causing stimulants.

Another reason why we feel Onnit Total Mitochondria is a great value for money is that they offer you a full 3-month money-back guarantee. Here’s what they write on their official website:

“If the product doesn’t perform for you, however, we’re not gonna play games with you. Order any of our entry size supplements, and if you don’t like it, you can keep it! Notify our team, telling us why it wasn’t a fit for you, and we’ll get you a refund right there on the spot – no return necessary. We just ask that you try it out for at least two weeks to give it a fair shot.”

Conclusion to Onnit Total Mitochondria Review

Onnit Total Mitochondria is not your typical energy enhancement supplement.

It optimizes your mitochondria which are your energy factories. What this does, is it gives you a supply of steady energy, as well as supporting your heart and general health.

The dosage is 1 capsule per day and the product will last you an entire month. The price of $50.99 is a great value for money in our experience, especially since you consider that you can email the company within 90 days for a full refund if you aren’t happy with the product.

Don’t let the ingredient label fool you; even though it only has 3 ingredients, Onnit Total Mitochondria is a complete energy and wellness formula that is especially useful if you’re past your 30s, as this is where our natural energy production capabilities start to wane.

You can find out more about Onnit Total Mitochondria here.


  1. Resveratrol. (source)
  2. Coenzyme Q10: The essential nutrient. (source)
  3. Pyrroloquinoline quinone. (source)

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